Overview

Omega-3 fish oil, which contains eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), has several potential health benefits, particularly in cardiovascular health.

Cardiovascular Benefits:

1. Reduction in Triglycerides: Omega-3 fatty acids are effective in lowering serum triglyceride levels, which is beneficial for patients with hypertriglyceridemia.

2. Anti-inflammatory Effects: Omega-3 polyunsaturated fatty acids have anti-inflammatory properties, which can help reduce the risk of atherosclerosis and other inflammatory cardiovascular conditions.

3. Plaque Stability: They may improve plaque composition and stability, reducing the risk of plaque rupture and subsequent cardiovascular events.

4. Cardiovascular Event Reduction: Some clinical trials have shown that omega-3 supplementation may reduce the incidence of major adverse cardiovascular events, particularly in high-risk populations.

Neuropsychiatric Benefits:

1. Brain Development: Omega-3 fatty acids are crucial for early brain development in infants.

2. Neuropsychiatric Disorders: They have been shown to benefit conditions such as dementia and depression.

General Recommendations:

The American Heart Association recommends the consumption of at least two servings of fatty fish per week to obtain adequate omega-3 intake. For individuals who cannot meet this dietary recommendation, omega-3 supplementation may be considered.

Dosage:

For cardiovascular benefits, particularly in patients with elevated triglycerides, a higher dose of omega-3 fatty acids (e.g., 4 grams/day of EPA) has been shown to be effective.

In summary, omega-3 fish oil provides significant benefits in reducing triglycerides, exerting anti-inflammatory effects, and potentially reducing cardiovascular events, with additional benefits in brain development and neuropsychiatric health.

References:

1. Cardiovascular Impact of Nutritional Supplementation With Omega-3 Fatty Acids: JACC Focus Seminar. Weinberg RL, Brook RD, Rubenfire M, Eagle KA. Journal of the American College of Cardiology. 2021;77(5):593-608. doi:10.1016/j.jacc.2020.11.060.
2. Seafood Long-Chain N-3 Polyunsaturated Fatty Acids and Cardiovascular Disease: A Science Advisory From the American Heart Association. Rimm EB, Appel LJ, Chiuve SE, et al. Circulation. 2018;138(1):e35-e47. doi:10.1161/CIR.0000000000000574.
3. Sea Change for Marine Omega-3s: Randomized Trials Show Fish Oil Reduces Cardiovascular Events. O'Keefe EL, Harris WS, DiNicolantonio JJ, et al. Mayo Clinic Proceedings. 2019;94(12):2524-2533. doi:10.1016/j.mayocp.2019.04.027.
4. Fish, Fish Oils and Cardioprotection: Promise or Fish Tale?. Goel A, Pothineni NV, Singhal M, et al. International Journal of Molecular Sciences. 2018;19(12):E3703. doi:10.3390/ijms19123703.

Benefits:

• Triglyceride reduction support
• Blood pressure support
• Plaque reduction support
• Cardiovascular health support
• Cognitive function support
• Mood support

How to Use:

 How: Take three (3) Veggie capsules once daily or as directed by a physician.

 When:

Once daily

 Serving Size:

Three (3) Capsules

 Ingredients:

Fish (Anchovy)

Gelatin

Glycerol

Water

Natural Lemon Flavor

May contain porcine